Georgetown University Medical Center

EH&S Newsletter

March, 1998

Susan Martin, Director

Sim Shanks, Radiation Safety Officer


Table of Contents

QUARTERLY HIGHLIGHTS
Phosgene from Chloroform
Fire Safety and Emergency Evacuation Plan
In The NEWS
Welcome Aboard
ASK EH&S
Know The Risk: Unmarried Men
Top 10 Most Frequent Radiation Safety Deficiencies in Fourth Quarter 1997
OSHA Cowboy
Applied Safety and Academics-(humor)

Radiation Safety Training Schedule

Send EH&S an email message


Phosgene from Chloroform

The spontaneous generation of dangerous quantities of phosgene (COCl2) from amylene preserved chloroform, stored properly in the absence of heat and light, has occurred in two brown glass containers in a UCLA laboratory. According to E. Turk (ACS Journal, March, 1998), "The chloroform was three years old when potentially lethal quantities of phosgene were discovered. Rather than a manufacturer specific problem, this oxidation is likely associated with alkene preservation and a catalytic contaminant."

An unusual darkening and unpleasant musty odor of an aqueous DNA phase during chloroform extraction were the first signs of a potential problem. Four lab personnel were sickened after smelling the chloroform. Analyses via several methods eventually confirmed phosgene. Headspace concentrations were measured as 15,000 ppm. The LD50 (inhalation) is a low 570 ppm per minute.

The author concludes, "The use of ethanol-preserved chloroform is desirable because ethanol, unlike alkenes, reacts quickly with phosgene. Furthermore, more ethanol than amylene is added commercially, providing extra protection against oxidations."

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Fire Safety and Emergency Evacuation Plan

The Office of the Dean of Research and Graduate Education (ODRGE) appointed members to the GUMC Fire Safety Task Force. The goal of the task force was to develop a comprehensive plan for the orderly evacuation of employees during a fire or similar emergency. Distribution of the completed plan to laboratories and GUMC departments began in February, 1998.

The Fire Safety and Emergency Evacuation Plan includes information such as procedures for reporting a fire, emergency evacuation procedures, Life Safety requirements, and building fire protection equipment. Staff are required to carefully review the plan to understand their responsibilities in the event of an emergency.

Important points of the plan include:

  • Know what to do prior to an evacuation.
  • Know who the Safety Partner/ Floor Marshall is for your floor.
  • Know your responsibilities as an employee and/or as a supervisor.
  • Know what to do when you hear an alarm.
  • Only telephone DPS (7-HELP) if you were the person that pulled the alarm.
  • Know the route of your first and second means of exiting the building.
  • Know the location of the assembly area for your building.

    It is GUMC policy that employees, students, and staff evacuate to the assembly area without attempting to fight the fire.

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    In The

    "Are Common Chemicals Scrambling Your Hormones?" Washington Times USA Weekend, 13-15 February 98, 18.
    The Environmental Protection Agency is increasing its research to determine whether synthetic chemicals cause reproductive and developmental problems, including falling sperm counts in men and early puberty in girls. Some researchers fear that chemicals in some shampoos, dyes, and detergents are absorbed through the skin and interfere with the hormonal system. The Chemical Manufacturers Association is also studying the problem. Sidebar: "Ways to Play It Safe" - offers tips for reducing your exposure to suspected hormone disruptors, and places to go for more information, including the following Web sites: (http://www.epa.gov/endocrine) and (http://www.wwfcanada.org/hormone-disruptors /index.html).

    "Hospital to End Radioactive Waste Practices [Metro in Brief: The District]" Washington Post, 3 March 98.
    The Nuclear Regulatory Commission announced that Washington Hospital Center has agreed to stop its improper handling of radioactive waste, including the unlicensed burning of radioactive waste in its incinerator.

    "Radon Blamed for 18,000 Lung Cancer Deaths in U.S. Each Year." Washington Post, 20 February 98. "Research Ties Radon to as Many as 21,800 Deaths Each Year." New York Times, 20 February 98.
    A panel from the National Research Council issued a report Thursday stating that radon is responsible for nearly 18,000 lung cancer deaths each year in the United States. About 90 percent of radon-related cancers occur in current or former smokers, and "most of the radon-related deaths among smokers would not have occurred if the victims had not smoked."

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    Welcome Aboard

    EH&S has recently hired a new employee, Theresa Farrell, to assist in the Occupational Safety Program. Theresa joined EH&S on March 2, 1998. A recent graduate from Slippery Rock University, Theresa earned a B.S. in Environmental Health and Safety.

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    ASK EH&S

    Why Would I Use a Secondary Container?
    Secondary containers are required when storing non-hazardous chemicals on the floor. Secondary containers prevent the release of spilled hazardous materials. Hazardous chemicals may not be stored on the floor even if inside secondary containers.

    What is a Secondary Container?
    A secondary container can be a plastic pan, beaker, bucket, tub, etc. that another container (the primary container) may be placed into. Secondary containers may not be glass.

    Where Do I Get a Secondary Container?
    EH&S (7-4712) has a wide variety of attractive colors.We saved a lot of money by purchasing kitty litter pans instead of costly labware.

    Is This a Rule or Just a Good Idea?
    This is a D.C. Fire Code requirement. Failure to comply has resulted in the issuance of costly fines.

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    Know The Risk: Unmarried Men

    The relative risk of being an unmarried man, expressed as the ratio of the mortality rates for unmarried men to married men.

    Cause of DeathSingleWidowedDivorced
    All Causes1.481.542.23
    Tuberculosis3.822.176.67
    Cancer
    Digestive
    1.251.261.55
    Respiratory
    1.161.262.13
    Genital
    0.951.231.37
    Leukemia1.191.081.21
    Diabetes1.461.411.92
    Stroke1.371.501.81
    Heart Disease1.321.461.77
    Cirrhosis of Liver2.572.426.22
    Motor Vehicle1.512.274.20
    All Other Accidents1.512.274.20
    Suicide1.532.394.08
    Homicide1.032.697.22
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    Top 10 Most Frequent Radiation Safety Deficiencies in Fourth Quarter 1997

    Rank Deficiency No. Deficiency Title
    1
    3.2.2
    Removable Survey Not Performed at Required Frequency
    2
    3.2.1
    Removable Survey Not Located at Time of Survey
    3
    3.3.1
    Meter Survey Not Performed or Not Documented
    4
    3.3.2
    Meter Survey Not Performed at Required Frequency
    5
    4.3.3
    Waste Containers Not Properly Labeled
    6
    2.6.2
    Training Not up to Date
    7
    3.2.3
    Wipes Not Taken in Random Locations
    8
    3.3.6
    Incorrect Meter Efficiencies or Information
    9
    2.5.3
    Empty Package Survey Prior to Disposal
    10
    2.5.2
    Wipe Test of Stock Vial Upon Receipt

    Every calendar quarter, the Radiation Safety Office Staff conducts an inspection of all laboratories authorized for the use of radioactive materials. The results of these radiation record reviews and physical surveys are communicated to the authorized users on a Laboratory Inspection Report form. The top 10 list represents the most frequently found deficiencies during fourth quarter inspections of 1997. Here is a brief explanation of the nature of the deficiencies, as well as the rationale behind the requirements.

    The four most prevalent deficiencies all relate to the performance and documentation of contamination surveys at the required minimum frequency. These surveys are a primary means of ensuring that there is not inadvertent radioactive contamination in and around areas where radioactive materials are used. These documented surveys, conducted at the required minimum frequencies, are an explicit condition of the institution's NRC license as well as the internal authorizations granted to RAM users. If survey responsibility is shared by numerous lab workers, a posted schedule or duty roster may be necessary. If one person routinely conducts the lab surveys, a substitute should be appointed to fulfill the duties in case of absence.

    4.3.3 Containers Not Properly Labeled
    Waste containers must be labeled with the following: -"Caution Radioactive Materials" -The name of the isotope it contains - "Aqueous" or "Organic" if it is a liquid

    Most occurrences of improper waste container labeling are liquid wastes which are not designated as either aqueous or organic .The distinction between the two types of liquids is important because organic liquids can never be disposed into the sanitary sewer system. Aqueous liquids are eventually disposed through controlled sink releases by the Radiation Safety Staff, after assuring that the release conforms to the appropriate regulatory requirements.

    2.6.2 Training Not up to Date
    The Authorized User Training Record documents that all staff in the laboratory have received training by the authorized user or a representative. Training includes bothhe specifics of using radioactive materials in that particular laboratory and general Georgetown University Radiation Safety policies. Deficiencies in this area include not documenting the training of all lab workers, both RAM and non-RAM, and also failure to provide a resignation date for workers no longer in the laboratory.

    3.2.3 Wipes Not Taken in Random Locations
    In addition to testing for removable contamination in all areas where radioactivity is used or stored, wipes must be taken in random locations. These random wipes ensure that areas in the laboratory that do not require regular wipe monitoring are not contaminated. Random wipes may be taken in any location in the laboratory. Common locations are items that get handled such as door knobs, telephones, computer keyboards, and equipment controls. Wipes should also be taken on the floor.

    3.3.6 Incorrect Meter Efficiencies or Information
    While it may often be treated like boiler plate, the meter efficiencies, detector types, serial numbers and calibration dates that appear on survey forms and personal contamination monitoring forms serve an important purpose. The meter readings that are recorded on these forms can only be understood within the context of the current calibrated meter efficiencies. Meter information must be changed whenever a meter is calibrated. If a substitute meter is used, the meter information must be recorded.

    2.5.3 Empty Package Survey Prior to Disposal
    2.5.2 Wipe Test of Stock Vial Upon Receipt

    These two deficiencies relate to the proper procedures for receiving radioactive material. After receiving radioactive material, a wipe test must be taken on the exterior of the stock vial prior to breaking the seal. The result of the wipe test should be entered on the designated area of the Radioactive Material Control Sheet and the counter printout must be attached. The box and the contents being disposed must be surveyed with a meter, and the results must also be documented on the Control Sheet. This process ensures that a leaking or contaminated stock vial is discovered immediately, before concentrated radioactive contamination is spread or disposed of in the trash.

    Please note that the empty package must also have all references to radioactive materials defaced prior to disposal.

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    OSHA Cowboy

    Click Here

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    Applied Safety and Academics

    Two trains are traveling towards each other on the same track. They are currently 25 miles apart. What happens next?

    The physics student: "It is a matter of (velocity * mass) * drag coefficient."

    The engineering student: "It is a matter of terrain, weather, track conditions, fuel supply and operator skill."

    The financing student: "Are all the passengers paid up?"

    The marketing student: "Can we still sell seats on the trains?"

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