Contents

Summary
Projects/Accomplishments
Professional Appointments
Academic
Honors/Awards
Research Expertise
Teaching/Mentoring
Other accomplishments...
Membership/Affil.
Invited Talks/presentation
Publications



Thanemozhi G. Natarajan, PhD

Summary:

  • Postdoctoral fellow with interests in comparative genomics, cell signaling, biomarker development..

Projects/Accomplishments:

Ø      Developed and validating a radiation induced cytogenetic method and p53 expression assay for assessing breast cancer risk.

Ø      Carried out extensive genotyping & VNTR polymorphism studies for various projects.

Ø      Experienced in writing for externally funded grants with ‘excellent’ rating.

Ø      Worked with clinical samples of fertility patients for clinical karyotyping and identified some rare translocations.

Ø      Reporting chromosomal rearrangements using conventional methods as well as modern software. Provided genetic counseling in cases where required.

Ø      Cytogenetic studies on clinical samples from congenitally malformed newborns and couples.

Ø      Papers in peer reviewed journals.

Professional Appointments:

  1. Post Doctoral Fellow, Lombardi Cancer Center; Georgetown Univ., Washington DC – 20007, Mar 2000 - Apr  2000

  2. Clinical Cytogeneticist, Infertility clinic (Pvt.) in Chennai (India), May 1999- Nov 1999.

Academic:

  1. 2000 - Ph.D. Zoology-Genetics, Madras University; Thesis work: Cytogenetic study on Congenital malformations…..

  2. 1992, M.Sc. Zoology, First class, Madras University

  3. 1990, B.Sc.  Zoology, First class, Madras University

 Honors/Awards:

1)      UGC-JRF Scholarship award (1993-1999) for pursuance of my research during my Ph.D. program.

2)      Proficiency Award in Zoology (1989) during my Undergraduate degree

 

Research expertise:

  • Cytogenetic: Cell culture techniques related to chromosomal preparations and conventional banding (GTG, CBG, AgNOR). Experienced in human karyotyping, diagnostic conventional cytogenetics and pedigree analyses. Good experience in mutagen sensitivity assays using chromosomal damage as end point.

  • Cell culture techniques: Well experienced in lymphocyte cultures and solid tissue culture,  (short- and long- term) and handling primary cultures and cell lines.

  • Molecular biology techniques: Experienced in molecular biology techniques related to genotyping using PCR and gel electrophoresis. Familiar with DNA sequencing and microsatellite analysis using ABI 377; p53 Western analyses, Cloning & expression, Northern and Southern analyses

 Teaching/Mentoring experience:

  1. Trained Lab personnel (technicians/graduate students) in the use of cytogenetic methods.

  2. Actively involved in guiding and mentoring M.Sc, M.Phil students towards their dissertation/theses.

  3. Guest lectures for Undergraduate students in Georgetown University, Biology department

  4. Taught credit courses in developmental genetics and cytogenetics M.Sc & M.Phil students in Madras University.

Other accomplishments/recognition:

  1. Refereed papers for peer reviewed journals.

  2. Featured in Nakkeeran , a Tamil magazine for a cover article on congenitally born babies.

Membership/Professional Affiliations:

  • American Association of Cancer Research

  • American Society of Preventive Oncology

  • Indian Society of Human Genetics

Invited talks/presentations

  1. 'Mutagen sensitivity as a biomarker for breast cancer: A study in African-American women'; Symposium on Breast Cancer & Racial Disparity; Sept 8th & 9th, Park Hyatt, Washington DC - 20037

Selected Publications/Papers presented:

  1. "Mutagen Sensitivity as a predictor of breast cancer risk in: A study in African-American women", Thanemozhi G. Natarajan, Peter G. Shields, Pamela Carter-Nolan, Cynthia A. Tucker and Lucille L. Adams-Campbell, Proceedings of the AACR, March 2003, Vol. 44, p 130

  2. “Mutagen sensitivity assay-A Validation Study”, Thanemozhi Govindan, Ramona Dumitrescu, Lindsey R Enewold, Xifeng Wu, Peter G Shields, Proceedings of the AACR, March 2003, Vol. 43,

  3. " Trisomy 4p and partial monosomy 18q due to paternal translocation t(4;18)(p11;q21.3)." Thanemozhi G., Santhiya S.T., Chandra N., Palka G., Jayam S. and Gopinath P.M. Indian J Pediatr. 67(8): 601-4, 2000.

  4. "A bisatellited supernumerary marker associated with recurrent spontaneous abortions. " Thanemozhi G., Santhiya S.T., Chandra N., Hannsmann I., Martin Th., and Gopinath P.M. Indian Journal of Human Genetics. 3(2): 71-76, 1997.

 

Presentations at Conferences

1)      “Recurrent Spontaneous abortions and Robertsonian Translocation t(13q14q)”. Annual Conference of Indian Society of Human Genetics, Dec 16 – Dec 18, 1997.

2)      An Epidemiological and Cytogenetics Study on Down’s syndrome. 22nd Annual Conference of Indian Society of Human Genetics, Jan 23 – Jan 25, 1995, Bangalore, India

3)      A Retrospective Study on Colorectal Cancer. XVI International Cancer Congress, Oct 30 – Nov 5, 1994, New Delhi, India